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Lipografting vs Steroid Injections for Treatment of Carpal Tunnel Syndrome

April 5, 2019


The regenerative properties of autonomous fat transfer to treat mild to moderate carpal tunnel syndrome are analyzed by this study in comparison to the current standard of care, corticosteroid treatment. Investigators hypothesize the transfer of fat will prevent scar formation and assist in nerve excursion along the canal.


Study Information

This is an interventional, non-randomized, double-blind, single group assignment of an estimated 100 participants. It includes an active comparator arm of a steroid injection and an experimental arm of injecting fat into subjects with carpal tunnel syndrome. This study will begin on December 19, 2019.


Inclusion Criteria

  • Individuals ages 18 and older are allowed to participate
  • They must have mild to moderate carpal tunnel syndrome (CTS)
  • Reported symptoms longer than 6 months including:
    • Night pain
    • Weakness
    • Sensory deficits
  • They must speak English fluently


Exclusion Criteria

  • Minors may not participate
  • Those who are non-English speaking
  • Have received an injection in the past 6 months
  • Had previous hand surgery or suffered previous hand trauma such as a fracture or dislocation



This trial will be conducted at Columbia University Medical Center in New York, New York.



This study is sponsored by Columbia University and the Principal Investigator Melvin P Rosenwasser, MD. This study will be conducted in collaboration with the Orthopaedic Scientific Research Foundation. Please contact Christina Freibott with any questions or concerns at 212-305-3912, or via email at

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